Outcomes of Sleep Disordered Breathing in Pregnancy
نویسندگان
چکیده
Sleep disordered breathing has been linked to adverse cardiovascular outcomes in the general population. In pregnancy, sleep disordered breathing has also been linked to pathologic disorders that have been associated with long term cardiovascular and metabolic outcomes such as gestational hypertensive disorders and gestational diabetes mellitus. Endothelial dysfunction, sympathetic stimulation and inflammation are among the mechanisms proposed to explain the association with adverse outcomes. In addition to mechanistic research, future efforts need to focus on the effect of therapy on such outcomes.
منابع مشابه
Sleep-disordered breathing during pregnancy.
Pregnancy is associated with many physiologic and hormonal changes along with changes in sleep architecture, placing pregnant women at risk for the development of sleep-disordered breathing or worsening of preexisting sleep apnea. Snoring, the most common symptom of sleep-disordered breathing, is markedly increased during pregnancy. The exact prevalence of obstructive sleep apnea in pregnant wo...
متن کاملSeverity of sleep-disordered breathing improves following parturition.
STUDY OBJECTIVE Changes in sleep-disordered breathing associated with late pregnancy have not previously been systematically investigated; however, a number of case reports indicate exacerbation of obstructive sleep apnea in late pregnancy, often in association with maternal hypertension. We aimed to compare the severity of sleep-disordered breathing and associated maternal blood-pressure respo...
متن کاملSleep disordered breathing in pregnancy
KEY POINTS Sleep disordered breathing (SDB) is common and the severity increases as pregnancy progresses.Frequent snoring, older age and high pre-pregnancy body mass index (>25 kg⋅m(-2)) could be reliable indicators for SDB in early pregnancy.SDB screening tools, including questionnaires, used in the nonpregnant population have poor predictive ability in pregnancy.Accumulating evidence suggests...
متن کاملSleep breathing disorders in pregnancy.
Snoring, upper airway resistance syndrome, sleep apnea syndrome and obesity hypoventilation syndrome are all defined as sleep-disordered breathing. Many changes occur in the respiratory system and sleep physiology during pregnancy due to physical and hormonal causes. Functional residual capacity, total sleep time, rapid eye movement (REM) sleep and stage 3-4 non-REM sleep are reduced during the...
متن کاملOCCASIONAL REVIEW Sleep disordered breathing and pregnancy
Many changes in the respiratory system occur during pregnancy, particularly during the third trimester, which can alter respiratory function during sleep, increasing the incidence and severity of sleep disordered breathing. These changes include increased ventilatory drive and metabolic rate, reduced functional residual capacity and residual volume, increased alveolar-arterial oxygen gradients,...
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